Kinetic performance in the gym hinges not only on the volume of work performed, but also on how efficiently the body can repair itself after each session. Many athletes reach a plateau when they neglect the biochemical processes that govern muscle recovery and inflammation. A small peptide called Lysine–Proline–Valine, or KPV, is emerging as an underrated tool for optimizing this very process. By targeting specific inflammatory pathways, KPV offers a natural alternative to traditional anti-inflammatory drugs without compromising muscle growth or performance.

KPV (Lysine–Proline–Valine) Peptide The Underrated Recovery Compound
The KPV peptide consists of three amino acids—lysine, proline and valine—in that order. Though it is only a tripeptide, its biological impact is surprisingly robust. Research has shown that KPV can bind to the formyl peptide receptor 2 (FPR2) on immune cells, modulating their response to injury or stress. When used as a supplement, KPV can be taken in capsule form, added to protein shakes, or incorporated into recovery protocols by athletes who want to reduce soreness and expedite tissue repair.

What Is KPV?
KPV is a naturally occurring peptide that acts as an anti-inflammatory agent at the cellular level. Unlike nonsteroidal anti-inflammatories that block prostaglandin synthesis systemically, KPV works locally by dampening the release of pro-inflammatory cytokines such as tumor necrosis factor alpha (TNF-α) and interleukin-1 beta (IL-1β). Its mechanism is rooted in competitive inhibition